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Article from THE AUSTRALIAN - 18 Nov 2006
Dental hygiene gives you a brush with cholesterolCraig O'Neill
A COMMON ingredient in toothpaste and mouthwash can cause high cholesterol and increase the risk of heart attack or stroke.
The bad news about the flavourless additive, called Poloxamer-407 (P407), comes from Victoria Cogger, a medical researcher with the Centre for Ageing and the ANZAC Research Institute in Sydney.
Her team found that when P407 was given to mice, it coated cells in the liver that control cholesterol levels, leading to a 10-fold increase in levels.
"There's a danger to keeping your cholesterol high ... this can lead to atherosclerosis (hardening of the arteries) over time," Dr Cogger said. This significantly increases the risk of heart attack, stroke or organ failure.
P407 is a detergent added to toothpaste and mouthwash to help mix the ingredients. Her team found that when P407 was given to mice, it coated cells in the liver that control cholesterol levels, leading to a 10-fold increase in levels.
